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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OPLAH All Species: 13.33
Human Site: T439 Identified Species: 26.67
UniProt: O14841 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14841 NP_060040.1 1288 137457 T439 T E V N S F L T N G P C P A S
Chimpanzee Pan troglodytes XP_528261 1212 130154 T439 T E V N S F L T N G P C P A S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539206 1379 147579 T536 T E V N S F L T N G P C P A S
Cat Felis silvestris
Mouse Mus musculus Q8K010 1288 137593 A439 M E V N S F L A S G P C P A S
Rat Rattus norvegicus P97608 1288 137702 T439 M E V N S F L T N G P C P A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521030 1300 139318 A450 A Q V N A F L A Q S P S P A G
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611675 1294 139594 K440 A E I N N Y L K S S G D N R V
Honey Bee Apis mellifera XP_001121487 1287 139635 A441 N Q I N E F L A K E G H G A K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794494 1307 142838 A446 A Q V N E F L A G Q E G N S R
Poplar Tree Populus trichocarpa XP_002305860 1269 137853 K447 N Q I N S Y R K S Q D S S A K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIZ7 1266 137512 K443 G Q I N I Y R K S Q D P S A K
Baker's Yeast Sacchar. cerevisiae P28273 1286 140409 N450 D V I N K D L N S N L T M E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 N.A. 69.4 N.A. 92.5 93.9 N.A. 80.2 N.A. N.A. N.A. N.A. 61.2 65 N.A. 64.1
Protein Similarity: 100 93.1 N.A. 74 N.A. 95.6 96.1 N.A. 87.2 N.A. N.A. N.A. N.A. 74.5 76.9 N.A. 76.1
P-Site Identity: 100 100 N.A. 100 N.A. 80 93.3 N.A. 46.6 N.A. N.A. N.A. N.A. 20 26.6 N.A. 26.6
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 93.3 N.A. 60 N.A. N.A. N.A. N.A. 46.6 40 N.A. 40
Percent
Protein Identity: 57.2 N.A. N.A. 56.8 49 N.A.
Protein Similarity: 70.9 N.A. N.A. 71.2 66 N.A.
P-Site Identity: 20 N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: 46.6 N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 0 0 9 0 0 34 0 0 0 0 0 75 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 42 0 0 0 % C
% Asp: 9 0 0 0 0 9 0 0 0 0 17 9 0 0 0 % D
% Glu: 0 50 0 0 17 0 0 0 0 9 9 0 0 9 9 % E
% Phe: 0 0 0 0 0 67 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 9 42 17 9 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 0 42 0 9 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 9 0 0 25 9 0 0 0 0 0 25 % K
% Leu: 0 0 0 0 0 0 84 0 0 0 9 0 0 0 0 % L
% Met: 17 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 17 0 0 100 9 0 0 9 34 9 0 0 17 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 50 9 50 0 0 % P
% Gln: 0 42 0 0 0 0 0 0 9 25 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 17 0 0 0 0 0 0 9 9 % R
% Ser: 0 0 0 0 50 0 0 0 42 17 0 17 17 9 42 % S
% Thr: 25 0 0 0 0 0 0 34 0 0 0 9 0 0 0 % T
% Val: 0 9 59 0 0 0 0 0 0 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _